How to Use Abreva: 15 Steps (with Pictures) - wikiHow (2025)

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  • Health
  • Infectious Diseases
  • Sexually Transmitted Diseases
  • Herpes Simplex Virus Infections
  • Cold Sores

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methods

1Applying the Cream

2Using the Product Safely

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Co-authored byDanielle Blinka, MA, MPAMedically reviewed byJanice Litza, MD

Last Updated: October 25, 2022References

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Cold sores can be painful and embarrassing, but fortunately there is an easy treatment for them. Abreva is the brand name of docosanol, an antiviral that treats the herpes simplex virus, which causes cold sores. Sold as a topical cream, Abreva can help relieve pain and discomfort caused by your cold sore and may help it to heal faster.[1] Applying Abreva is easy, but you do need to use it several times a day and should follow basic safety precautions.

Things You Should Know

  • Wash the area before applying a dab to the cold sore, and rub the medicine in with a gentle touch.
  • Apply Abreva 5 times per day, washing your hands after; only apply other products after it dries and avoid kissing loved ones while using it.
  • Talk to your doctor before using Abreva, especially when using it on a child, and avoid sharing it as cold sores are contagious.

Method 1

Method 1 of 2:

Applying the Cream

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  1. 1

    Use the medication as soon as you start experiencing symptoms. Early signs of a coming cold sore include pain, burning, or feeling the blister emerging.[2]

    • Abreva is made for use on your face or around your lips, but you can also use it around your nostrils if your cold sores have extended there. Don't apply it inside your nose or mouth.
    • If a small amount gets into your mouth, such as cream that you licked off your lips after application, there is no need to worry. It is not harmful in small amounts.[3]
  2. 2

    Wash the area before applying the product for best results. Start by washing your hands with soap and water, then remove any makeup. Cleanse the area with soap or cleanser and warm water. Lightly pat the area dry with a clean towel.[4]

    • You may want to use a paper towel or napkin to blot away the water so that you can throw it away afterwards. You don't want to use the same towel on unaffected skin, as you can spread the virus.

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  3. 3

    Apply a dab of Abreva on top of the cold sore. Use your finger or a cotton swab to cover your cold sore with the cream. You should apply a generous amount to be sure that the whole sore is treated. Don't worry if you get the cream on your unaffected skin, as the medicine is safe on both healthy skin and cold sores.[5]

  4. 4

    Rub the medicine into your cold sore using a light touch. Gently massage the cream into your sore until it is fully absorbed. You should not have a remaining white residue[6]

  5. 5

    Wash your hands after treatment to avoid sharing the virus. Use soap and warm water to clean the virus from your hands. Herpes simplex 1 is highly contagious and can possibly spread to other parts of your body or to loved ones.[7]

  6. 6

    Continue applying the medicine 5 times a day until your sore has healed. Use the medicine every 3 to 4 hours for up to 10 days. If your sore has not healed after that period, talk to your doctor about what you should do.[8]

    • If you are using the Abreva on a child under 12, ask your doctor for a dosage recommendation.[9]
  7. 7

    Apply other products only after the Abreva dries. It's okay to wear makeup over the cold sore, but don't apply it directly from the container. Use a separate applicator like a cotton swab avoid contaminating your product, which could allow the virus to spread.[10]

  8. 8

    Avoid kissing loved ones while using the product. Since the virus that causes cold sores is so contagious, don't allow anyone to come into contact with the sore. Kissing or snuggling others could infect them. While the virus is most common around the mouth, it's important to remember that it can spread to other parts of the body.[11]

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Method 2

Method 2 of 2:

Using the Product Safely

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  1. 1

    Talk to your doctor before you use Abreva. You should always discuss possible treatments with your doctor before you try a new medication. They can tell you if Abreva is right for you. Tell your doctor about the other medications you are taking, as well as if you are allergic to any medications, foods, dyes, preservatives, or animals.

    • Abreva can interact with other medications, both prescription and over-the-counter.
    • If you are allergic to Abreva, you should not take it.[12]
    • Talk to your doctor if you are pregnant or nursing.[13]
  2. 2

    Be careful when using the medication on children. Abreva is not recommended for use on children under 12 without approval from a doctor. While the medication has not been shown to harm children, it's always a risk to give medication to children, so you will need a doctor's supervision.[14]

  3. 3

    Avoid sharing your medication, as cold sores are contagious. Abreva comes in a tube or a pump, and either container can pose a risk if shared. Even if you use a separate applicator, like a cotton swab, your container can still be contagious.[15]

  4. 4

    Avoid putting the medicine near your eyes or around your genitals. Abreva is only approved for use on your face. Consult your doctor for treatments in other parts of your body.[16]

    • If the virus has affected your eye area, you will need to see a doctor for prescription anti-viral eye drops.[17]
    • The medications used to treat genital herpes are called Valtrex and Zovirax. These are usually available by prescription. You can also take these medications for cold sores, and they are safe to use in combination with Abreva.
    • If you get it in your eyes, flush them with water.
  5. 5

    Expect possible side effects that usually don't require treatment. You may experience no side effects. Even if you do experience any, you may find that they go away as you adjust to the medicine. If the side effects continue or are difficult to handle, see your doctor. Side effects to watch for include:[18]

    • Headache
    • Acne
    • Burning
    • Dryness
    • Itching
    • Rash
    • Redness
    • Soreness
    • Swelling
  6. 6

    Check the expiration date before applying the product. You should not keep expired products in your cabinet, but sometimes you might forget to check the dates regularly. Before you use leftover product, make sure it hasn't expired. If it has, it may not be as effective.[19]

  7. 7

    Keep the product where children and pets can't reach it. Abreva can be dangerous if ingested or misapplied by children and pets. Place it in a secure, unreachable location.[20]

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      More References (11)

      1. https://www.abreva.com/cold-sore-products/how-to-use-abreva-cream/
      2. https://www.abreva.com/faq/how-to-use-abreva/
      3. http://www.mayoclinic.org/drugs-supplements/docosanol-topical-route/before-using/drg-20063494
      4. https://www.abreva.com/faq/how-to-use-abreva/
      5. http://www.mayoclinic.org/drugs-supplements/docosanol-topical-route/before-using/drg-20063494
      6. https://www.abreva.com/cold-sore-products/how-to-use-abreva-cream/
      7. http://www.mayoclinic.org/drugs-supplements/docosanol-topical-route/before-using/drg-20063494
      8. https://www.mayoclinic.org/diseases-conditions/keratitis/basics/treatment/con-20035288
      9. http://www.mayoclinic.org/drugs-supplements/docosanol-topical-route/side-effects/drg-20063494
      10. http://www.mayoclinic.org/drugs-supplements/docosanol-topical-route/before-using/drg-20063494
      11. http://www.mayoclinic.org/drugs-supplements/docosanol-topical-route/before-using/drg-20063494

      About This Article

      How to Use Abreva: 15 Steps (with Pictures) - wikiHow (26)

      Medically reviewed by:

      Janice Litza, MD

      Board Certified Family Medicine Physician

      This article was medically reviewed by Janice Litza, MD and by wikiHow staff writer, Danielle Blinka, MA, MPA. Dr. Litza is a Board Certified Family Medicine Physician based in Racine, Wisconsin. With over 25 years of educational and professional experience, she has extensive experience providing full-spectrum Family Medicine, including obstetrics, newborn care, and hospital medicine. She is currently the Residency Program Director for Family Medicine at Ascension. Dr. Litza received her MD from the University of Wisconsin-Madison School of Medicine and Public Health and has completed additional fellowship training in Integrative Medicine through the University of Arizona. This article has been viewed 82,225 times.

      55 votes - 90%

      Co-authors: 10

      Updated: October 25, 2022

      Views:82,225

      Categories: Cold Sores

      Medical Disclaimer

      The content of this article is not intended to be a substitute for professional medical advice, examination, diagnosis, or treatment. You should always contact your doctor or other qualified healthcare professional before starting, changing, or stopping any kind of health treatment.

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      Reader Success Stories

      • How to Use Abreva: 15 Steps (with Pictures) - wikiHow (27)

        Ray Fuller

        Aug 6, 2020

        "I have used abreva several times with very good results."

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      How to Use Abreva: 15 Steps (with Pictures) - wikiHow (2025)

      FAQs

      How to use Abreva correctly? ›

      Wash and dry your hands before applying the medication. Clean and dry the affected areas. Apply a thin layer of medication to completely cover the area of the cold sore or the area of tingling/itching/redness/swelling and rub in gently, usually 5 times a day every 3-4 hours, or as directed by your doctor.

      Can you put too much Abreva on a cold sore? ›

      Applying more than necessary shouldn't cause problems, but it won't help, either. You should carefully follow all product instructions for use, as provided on the package and as directed by your healthcare provider. Abreva should not be used on mucosal or sensitive areas, such as inside the nose or mouth.

      What stage do you stop using Abreva? ›

      Once the scab has formed, your cold sore is almost completely healed. Keep applying Abreva® Cream for 10 days or until the scab has fallen off, whichever comes first.

      Is it better to keep a cold sore scab wet or dry? ›

      Keeping a cold sore clean and dry while it heals is critical. From the time it appears until a scab form, keep the area dry. However, keeping the area moist during scabbing can improve discomfort and lessen the likelihood of painful splitting or cracking.

      How many days in a row can I use Abreva? ›

      Abreva® Cream can be used by adults and children over 12 years old. It should be used five times a day for up to 10 days. And because cold sores are contagious, you won't want to share your tube of Abreva® Cream with others. Doing so may spread the infection.

      Does Abreva still work after the blister appears? ›

      Does Abreva® Work After the Blister Appears? Abreva® Cream should be used at the first sign of a cold sore for the best results. Using it after blisters appear will affect its efficacy.

      How to dry up a cold sore in hours? ›

      Docosanol (Abreva) is an over-the-counter cream for cold sores. It must be applied frequently and may shorten an outbreak by a few hours or a day. Try other cold sore remedies. Some over-the-counter preparations contain a drying agent, such as alcohol, that may speed healing.

      Does Abreva speed up healing? ›

      Abreva® cold sore cream can heal a cold sore in as few as 2½ days* when used at the first sign of an outbreak. Nothing heals a cold sore faster. Abreva® Cream contains the only non-prescription ingredient approved by the FDA to shorten the time it takes to get rid of a cold sore.

      How do you reduce the size of a cold sore fast? ›

      There are antiviral drugs that can help cold sores heal faster, including acyclovir, valacyclovir, famciclovir and penciclovir. If you're having frequent outbreaks or experiencing some of the serious side effects of having a cold sore, your doctor may consider prescribing antiviral medication.

      What stage of abreva is a scab? ›

      Stage 4: SCAB FORMATION

      Your burst blister will dry out, forming a yellow-brown scab. Although this is unsightly, it's a sign that your cold sore has begun healing. As the scab shrinks, it may create painful cracks in your lip that bleed. The area may itch, burn, or feel tight.

      When is cold sore no longer infectious? ›

      How long are cold sores contagious for? Cold sores, caused by a type of virus called herpes simplex type 1, are contagious until they completely go away, which usually takes about two weeks. Cold sores are the most contagious when fluid seeps out of the sores.

      What's the longest a cold sore should last? ›

      Cold sores usually last one to two weeks. Symptoms may be more severe and sores may take longer to heal if you're immunocompromised.

      Is it better to cover a cold sore or let it breathe? ›

      You should probably skip covering it up if you have an open cold sore because that could cause it to get infected. It's best to wait for a cold sore to become partially healed and scabbed over before trying to cover it up.

      Is vaseline good for cold sores? ›

      A petroleum jelly such as Vaseline won't necessarily heal a cold sore, but it may ease discomfort. The jelly helps prevent cracking. It also serves as a protective barrier against outside irritants. Witch hazel is a natural astringent that may help dry out and heal cold sores, but it can sting with application.

      Does toothpaste help with cold sores? ›

      There is little evidence to support the use of toothpaste as a treatment for cold sores. While there are success stories, they don't add up to solid proof. Toothpaste additives like SLS may have antiviral properties, but they can also irritate skin or cause allergic reactions, which can make problems worse.

      How long does Abreva take to work? ›

      ABREVA CAN GET RID OF COLD SORES IN 2.5 DAYS* SO YOU CAN GET BACK TO BEING YOU. *When used at the first sign. Median healing time 4.1 days. 25% of users healed by 2.5 days.

      Why does Abreva work so fast? ›

      Abreva works quickly by penetrating deep into the skin to the source of the spreading virus.

      How to get rid of a cold sore in 24 hours? ›

      It is not possible to get rid of a cold sore quickly, as there is currently no cure for HSV-1. In most cases, cold sores heal in 5–15 days without treatment. Antiviral medication may speed the healing process by about 1 day .

      What is the difference between Abreva tube and pump? ›

      The tube is perfect to use at home while the pump offers a clean and easy way to carry your Abreva® Cream on the go, so you're ready to fight at the first tingle.

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